During exercise, isolated premature ventricular complexes or contractions (PVCs) occur in what percentage of healthy subjects?

Isolated premature ventricular complexes (PVCs) during exercise can be a common occurrence in healthy individuals, particularly during periods of increased physical stress or exertion. Research indicates that a significant percentage of healthy subjects, often in the range of 30 to 40%, may demonstrate these isolated PVCs during exercise. This phenomenon can result from a variety of physiological factors, including increased sympathetic nervous system activity and changes in electrolytes or autonomic tone during vigorous activity.

Understanding that PVCs in this percentage range are typically benign in well-conditioned athletes helps to reassure both participants and healthcare professionals that, while they might be seen frequently, they do not necessarily indicate underlying cardiovascular disease in the absence of other symptoms or risk factors.